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Detailed Introduction
The Agilent 6120 Single Quadrupole LC/MS System is a reliable and cost-effective liquid chromatography mass spectrometry platform designed for routine qualitative and quantitative analysis. It combines Agilent’s proven LC technology with single quadrupole mass detection, providing laboratories with a simple, robust, and easy-to-maintain solution for pharmaceutical, chemical, environmental, food, and biological applications.
The Agilent 6120 LC/MS uses a single quadrupole mass analyzer to deliver fast scanning, stable performance, and excellent sensitivity for compound identification and confirmation. It supports electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI), allowing analysis of a broad range of polar and non-polar compounds.
With Agilent MassHunter software, the system provides intuitive instrument control, data acquisition, qualitative analysis, and reporting functions. It is widely used for impurity identification, reaction monitoring, quality control, and routine screening applications.
The compact design and dependable operation of the Agilent 6120 make it an ideal choice for laboratories looking for an affordable LC/MS solution. Used Agilent 6120 LC/MS systems are especially popular due to their durability, availability of spare parts, and compatibility with Agilent 1200/1260 LC systems.
| Parameter | Specification |
|---|---|
| Instrument Type | Single Quadrupole Liquid Chromatography Mass Spectrometer |
| Manufacturer | Agilent Technologies |
| Model | Agilent 6120 LC/MS |
| Mass Analyzer | Single Quadrupole |
| Mass Range | m/z 2–2000 |
| Resolution | Unit mass resolution |
| Ionization Source | Electrospray Ionization (ESI) / APCI |
| Ion Modes | Positive and Negative Ion Modes |
| Scan Speed | Up to 10,000 amu/s |
| Mass Accuracy | Typically within ±0.1 Da |
| LC Compatibility | Agilent 1100 / 1200 / 1260 LC Systems |
| Software | Agilent MassHunter Workstation |
| Detector Type | Quadrupole Mass Filter Detector |
| Applications | Pharmaceutical analysis, environmental testing, food safety, chemical analysis |
| Sample Analysis | Small molecules, metabolites, impurities, additives |
| Vacuum System | High-performance turbomolecular pumping system |
| Interface | Atmospheric pressure LC/MS interface |
| Operation Mode | Full Scan, SIM (Selected Ion Monitoring) |
| Main Advantages | Reliable operation, easy maintenance, economical ownership |
The Agilent 6120 Single Quad LC/MS System is a practical choice for laboratories requiring dependable LC/MS performance for everyday analytical workflows. Its combination of simplicity, robustness, and affordability makes it a widely used instrument in research institutions, quality control laboratories, and industrial testing facilities.
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