Beckman Coulter Allegra X-14 Centrifuge with SX4750 Rotor, 4 Buckets and 4× Plate Holder – Product Introduction

The Beckman Coulter Allegra X-14 Centrifuge equipped with the SX4750 swing-bucket rotor, 4 buckets, and 4× microplate holders is a versatile, high-capacity benchtop centrifuge system designed for routine clinical, molecular biology, and bioprocessing workflows. It combines reliable medium-speed performance with flexible rotor configurations, making it a widely used platform in research laboratories, biotechnology facilities, and diagnostic environments.

This configuration is particularly valuable for laboratories requiring both tube-based and microplate-based centrifugation, enabling seamless switching between sample formats without changing core instruments.

High-Performance Benchtop Centrifugation System

The Allegra X-14 is engineered to deliver consistent and reproducible centrifugal force for everyday laboratory applications. With the SX4750 swing-bucket rotor installed, the system achieves a maximum speed of approximately 4,750 rpm and a maximum relative centrifugal force (RCF) of up to 5,250 × g, depending on configuration.

This performance range is ideal for cell pelleting, protein precipitation, nucleic acid preparation, and routine sample clarification. The swing-bucket rotor design ensures that samples remain horizontal during acceleration, providing improved phase separation and higher pellet quality compared to fixed-angle systems.

SX4750 Swing-Bucket Rotor System

The included SX4750 rotor is a high-capacity swing-bucket rotor featuring 4 buckets with up to 750 mL capacity per bucket, enabling a total processing capacity of up to 3,000 mL per run. This makes it suitable for medium-throughput workflows involving large-volume biological samples.

The rotor supports a wide range of adapters, including:

• Standard centrifuge tubes

• Cell culture flasks

• Blood collection bags

• Bottles and large-volume containers

• Microplate carriers (4-position plate holder configuration)

The 4× plate holder system allows simultaneous processing of multiple microtiter plates, significantly improving workflow efficiency in high-throughput screening, ELISA sample preparation, and diagnostic assays.

The rotor is constructed from high-strength aluminum and stainless steel, ensuring durability, chemical resistance, and long service life under repeated centrifugation cycles.

Flexible Application Capability

The Allegra X-14 with SX4750 rotor system is designed for broad laboratory applications, including:

• Cell harvesting and pelleting

• Bacterial and yeast culture processing

• DNA/RNA extraction workflows

• Protein precipitation and clarification

• Blood and plasma separation

• High-throughput microplate centrifugation

• General sample preparation in clinical laboratories

Its flexibility makes it a core instrument for laboratories that require both large-volume centrifugation and microplate-based workflows in a single platform.

User-Friendly Operation and Workflow Efficiency

The system is designed with an intuitive digital interface that allows users to easily set and monitor speed, time, and operational parameters. The display provides clear feedback on running conditions, ensuring reproducibility across experiments.

Key operational features include:

• Programmable speed and time control

• Rapid acceleration and braking profiles

• “Quick Run” function for short spin-downs

• Easy rotor recognition and configuration

The swing-bucket design ensures stable load distribution and smooth operation, reducing vibration and enhancing sample integrity.

Safety and Reliability

Safety is a critical design element of the Allegra X-14 system. It incorporates multiple protective mechanisms to ensure secure operation:

• Lid interlock system prevents operation when the lid is open

• Imbalance detection automatically stops the run if uneven loading occurs

• Rotor overspeed protection ensures safe operating limits

• Biocontainment-compatible bucket systems (depending on configuration)

These safety features make the system suitable for both research and clinical laboratory environments where biosafety compliance is required.

Robust Mechanical Design

The centrifuge is built for long-term durability with a heavy-duty motor system and reinforced internal structure. The SX4750 rotor’s swing-bucket mechanism ensures smooth motion and minimizes mechanical stress on samples.

The system is engineered for continuous daily use, with low maintenance requirements and stable performance even under frequent loading and unloading cycles.

Efficiency and Laboratory Productivity

By supporting both high-volume tube centrifugation and multi-plate processing, the Allegra X-14 system significantly improves laboratory efficiency. Researchers can process different sample types without switching instruments, reducing downtime and increasing throughput.

This makes it especially valuable in:

• Core laboratories

• Clinical diagnostic labs

• Biotechnology production labs

• Academic research facilities

Technical Specifications