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Detailed Introduction
The Agilent 6470 Triple Quadrupole LC/MS System is a next-generation tandem mass spectrometry platform designed for high-sensitivity quantitative analysis and demanding analytical workflows. It combines Agilent’s advanced triple quadrupole technology with enhanced ion optics and Agilent Jet Stream (AJS) Electrospray Ionization to deliver exceptional sensitivity, selectivity, accuracy, and reproducibility for complex sample analysis.
The Agilent 6470 Triple Quad LC/MS features a highly efficient QqQ mass analyzer optimized for Multiple Reaction Monitoring (MRM) applications. The first quadrupole selects the precursor ion, the collision cell generates product ions, and the third quadrupole detects specific fragment ions. This configuration enables reliable quantification of trace-level compounds in challenging matrices, making it suitable for pharmaceutical development, clinical research, environmental testing, food safety, forensic analysis, and metabolomics studies.
The system provides improved ion transmission efficiency, wider dynamic range, and excellent signal stability, allowing laboratories to achieve lower detection limits and higher analytical confidence. It supports advanced workflows such as targeted quantitation, impurity analysis, biomarker detection, and multi-component screening.
Controlled by Agilent MassHunter Workstation Software, the 6470 provides comprehensive functions for instrument control, method optimization, quantitative analysis, and data reporting. It can be integrated with Agilent Infinity II LC systems to create a powerful LC-MS/MS analytical platform.
The Agilent 6470 Triple Quadrupole LC/MS System is widely recognized for its outstanding sensitivity, robustness, and productivity, making it an excellent solution for laboratories requiring reliable high-performance quantitative mass spectrometry.
| Parameter | Specification |
|---|---|
| Instrument Type | Triple Quadrupole Liquid Chromatography Tandem Mass Spectrometer |
| Manufacturer | Agilent Technologies |
| Model | Agilent 6470 Triple Quad LC/MS |
| Mass Analyzer | Triple Quadrupole (QqQ) |
| Mass Range | m/z 5–3000 |
| Ion Source | Agilent Jet Stream Electrospray Ionization (AJS ESI) |
| Ionization Modes | Positive and Negative Ion Modes |
| Quantitation Technology | Multiple Reaction Monitoring (MRM) |
| Collision Cell | High-performance collision cell |
| Sensitivity | Ultra-high sensitivity for trace compound detection |
| Dynamic Range | Wide quantitative dynamic range |
| LC Compatibility | Agilent 1290 Infinity II LC System |
| Software | Agilent MassHunter Workstation Software |
| Acquisition Modes | MRM, Product Ion Scan, Precursor Ion Scan |
| Applications | Pharmaceutical analysis, clinical research, food safety, environmental testing |
| Sample Types | Drugs, metabolites, biomarkers, pesticides, biological samples |
| Detector Type | Triple Quadrupole Mass Detector |
| Key Advantages | High sensitivity, excellent selectivity, fast analysis, reliable quantitation |
The Agilent 6470 Triple Quadrupole LC/MS System represents a powerful solution for modern analytical laboratories, providing the sensitivity and performance required for accurate quantitative analysis of increasingly complex samples.
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